| 학회 |
한국고분자학회 |
| 학술대회 |
2017년 봄 (04/05 ~ 04/07, 대전컨벤션센터) |
| 권호 |
42권 1호 |
| 발표분야 |
대학원생 구두발표 (발표15분) |
| 제목 |
Development of Anti-Biofouling Plasma Filtration Membrane by Electrospinning Process Using Photo-Crosslinkable Zwitterionic Polymers |
| 초록 |
The purpose of this research is to fabricate anti-biofouling plasma filtration membrane with average pore diameter of less than 2μm via electrospinning process. In order to achieve this, random-type terpolymer consisting of zwitterionic phosphorylcholine (PC) group and UV-crosslinkable phenyl azide group was synthesized. Zwitterionic PC group was adopted for providing anti-biofouling property and phenyl azide group was chosen as stable crosslinker for hydrophilic PC group in aqueous medium. The membrane containing zwitterionic PC group showed remarkably decreased protein adsorption and platelet adhesion. The membrane’s blockage resulting from the platelet adhesion was analyzed by the BET experiment. The filtration performance of the prepared membrane was tested by filtering Platelet-Rich-Plasma solution, and 95% of platelet was filtered by the prepared membrane. In conclusion, UV-crosslinkable zwitterionic polymer is useful in preparing anti-biofouling blood-filtration membrane. |
| 저자 |
서지애, 서지훈
|
| 소속 |
고려대 |
| 키워드 |
plasma filtration; zwitterion; UV-crosslinkable; protein adsorption; platelet adhesion
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| E-Mail |
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