| 학회 |
한국공업화학회 |
| 학술대회 |
2014년 봄 (04/30 ~ 05/02, 제주국제컨벤션센터) |
| 권호 |
18권 1호 |
| 발표분야 |
포스터-나노 |
| 제목 |
A High-Performance Platelet-Derived Growth Factor Aptamer Functionalized Hybrid Carbon Nanofiber Biosensor |
| 초록 |
The highly sensitive field-effect transistor (FET) system biosensor to detect platelet-derived growh factor (PDGF) was fabricated using carboxylic polypyrrole coated metal oxide decorated carbon nanofibers (CPMCNFs) and PDGF-B binding aptamer. CPMCNFs were fabricated using metal oxide decorated carbon nanofibers (MCNF) and carboxylic polypryrrole monomer via vapor deposition polymerization (VDP). CPMCNFs were integrated with PDGF-B binding aptamer and immobilized on the IDA substrate by covalent anchoring. The CPMCNFs-PDGF-B binding aptamer (CPB-Apt) FET sensor are highly sensitive and precise selective toward isoform of PDGFs. Additionally, the CPB-Apt FET sensor shows the re-usability in few weeks. |
| 저자 |
전재문, 이준섭, 장정식
|
| 소속 |
서울대 |
| 키워드 |
biosensor; carbonnanofiber; PDGF
|
| E-Mail |
|
