화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2019년 봄 (04/10 ~ 04/12, 부산컨벤션센터(BEXCO))
권호 44권 1호
발표분야 기능성 고분자
제목 Impartment of antibiofouling properties to macro and nanoscale gold sufaces by utilizing simple synthesis and coating method of sulfobetainic zwitterionic small molecule.
초록 The goal of this study is to develop a one-pot synthesis of a zwitterionic small molecule and use it as an effective anti-biofouling coating material on macro and nanoscopic gold surfaces. To this end, a zwitterionic small molecule was successfully synthesized by a one-pot method using dipyridyl disulfide. The coating conditions and stability were examined through contact angle measurements, surface plasmon resonance (SPR), X-ray photoelectron spectroscopy. The anti-biofouling properties of the coated gold surface were analyzed by FITC-bovine serum albumin (BSA) test and SPR as contacting with BSA solution. In addition, the effect of zwitterion-coating on stability of and protein adsorption on gold nanoparticles were examined through a NaCl stability test and BSA adsorption test, respectively. As a result, simply synthesized zwitterionic small molecule effectively enhanced the anti-biofouling properties gold surfaces and the salt stability of gold nanoparticles.
저자 이승주1, 이원규1, 박지호2, 이재승1, 서지훈1
소속 1고려대, 2서강대
키워드 small molecule; protein adsorption; zwitterion; anti-biofouling; gold substrate; gold nanoparticle; salt stability
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