| 초록 |
In this study, we describe a simple method for fabricating multiscale scaffolds that are capable of controlling the spatial positioning of mammalian cells and proteins. Photopatterning of poly(ethylene glycol)(PEG) hydrogel on the electrospun nanofibers produced micropatterned nanofiber matrices made of hydrogel microwells filled with a nanofibrous region, which is capable of generating cell and protein micropatterns due to the different interactions that cells and proteins have with PEG hydrogels and nanofibers as shown in Figure 1. Different proteins and could be immobilized onto resultant micropatterned nanofiber scaffold, carrying out cell patterning, metabolite detection, and growth factor delivery |
