| 학회 |
한국공업화학회 |
| 학술대회 |
2007년 가을 (11/02 ~ 11/03, 한경대학교) |
| 권호 |
11권 2호 |
| 발표분야 |
고분자 |
| 제목 |
Preparation and NMR spectroscopic characterization of low molecular weight water soluble N,O-carboxymethyl chitosan |
| 초록 |
N,O-Carboxymethyl chitosan(N,O-CMCh) of biocompatible derivatives of chitosan was prepared by chemical reaction with mono-chloroacetic acid and glyoxylic acid on low molecular water soluble chitosan(LMWSC) of C6 position -OH and C2 position -NH2 group to apply as cationic drug carrier. The substitution of carboxymethyl groups on 6-O and 2-N can be determined by 1H-NMR. Degree of substitution (DS) and degree of deacetylation(DDA) of O-sCMCh were 96%, 98%(6-O) and 45%(2-N) respectively. DS of the C6 -OH group had higher than C2 -NH2. |
| 저자 |
정현, 남정표, 장학수, 허선행, 김동곤, 정영일, 박준규, 장민자, 서동혁, 장미경, 나재운
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| 소속 |
순천대 |
| 키워드 |
N; O-carboxymethyl chitosan; Water-soluble chitosan; NMR; HMQC; DEPT
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| E-Mail |
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