| 초록 |
Design and construction of synthetic co-culture is an appropriate strategy to enhance the performance of sustainable biorefinery process using a recalcitrant substrate such as carbon monoxide (CO). The biological conversion of CO has been highlighted to develop practical applications for production of valuable chemicals. In this study, we examined an artificial microbial consortium consisting of Citrobacter amalonaticus Y19 and Sporomusa ovata for acetate production from CO as the sole external carbon source. In this consortium, CO2 and H2 produced by water-gas shift reaction of C. amalonaticus Y19 were further utilized by S. ovata for acetate production. As a result, the higher acetate production was obtained in co-culture system as compared to monoculture counterpart. Furthermore, the syntrophic cooperation between two different species provided new insight into electron transfer mechanism, as well as synergistic metabolic benefit in toxic substrate such as CO. |
