화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2010년 봄 (04/08 ~ 04/09, 대전컨벤션센터)
권호 35권 1호
발표분야 의료용 고분자 부문위원회
제목 Evaluation of PEG/PVA Hydrogels Prepared by a Freezing-Thawing Method and Gamma-Ray Irradiation
초록 Poly(vinyl alcohol) (PVA) and polyethylene glycol (PEG) are excellent candidates as biomaterials because of their inherent water-soluble, non-toxic, and biocompatible properties. Gamma-rays have been used to cross-link and sterilize the biomaterials instead of a cross-linking agent and heating method which influence the mechanical properties of biomaterials. In this work, to improve the mechanical strength of the PVA hydrogel, the PEG was blended with PAG in water. The PEG/PVA hydrogels were prepared by using a freezing-thawing method and gamma-ray irradiation technique. The prepared hydrogels were characterized by measuring physical properties such as gel content, hydration, FTIR, and TGA analysis. The enhanced mechanical strength of the PEG/PVA hydrogels was confirmed by using compressive strength. It was also confirmed that the PEG/PVA hydrogels were non-toxic by using a cell count kit-8 (CCK-8) assay.
저자 조선영1, 김용수1, 권희정1, 박종석1, 신흥수2, 임윤묵1, 노영창1
소속 1한국원자력(연), 2한양대
키워드 PEG; PVA; hydrogel; gamma-ray; freeze-thaw
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