| 학회 |
한국공업화학회 |
| 학술대회 |
2013년 가을 (10/30 ~ 11/01, 대전컨벤션센터) |
| 권호 |
17권 2호 |
| 발표분야 |
포스터-고분자 |
| 제목 |
Silica nanoparticles attachment onto PEO-PLA core-shell fiber by “Electrohydrodynamic Jetting of Countercharged nozzles” for drug release control |
| 초록 |
In this study, we prepared SiO2 nanoparticles attached core-shell fibers by EJC. OM & SEM images reveal smooth (bead free) surfaces of core-shell (PEO-PLA) fibers with physically attached SiO2 nanoparticles. The release test of rhodamine-B loaded in PEO phase was studied using UV-visible spectroscopy. The physically attached SiO2 particles were embedded into core-shell fibers by solvent vapor annealing (SVA) with different times. It concluded that 20 mins of SVA gave half embedded SiO2 particles. The socket type structure was observed on the surface of core-shell fiber after detaching the silica nanoparticles. In particular, we proposed a strategy for on-off drug release systems. By sonication, SiO2 particles can be detached from core-shell fibers with possible release control of dye. This work suggests one possible approach for controlled release of such actives using SiO2 particles attached core-shell fibers. |
| 저자 |
Mallinath, 이종휘
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| 소속 |
중앙대 |
| 키워드 |
; PEO; Silica particles; Drug release; Co-axial electrospinning and EJC
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| E-Mail |
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