| 학회 |
한국고분자학회 |
| 학술대회 |
2009년 봄 (04/09 ~ 04/10, 대전컨벤션센터) |
| 권호 |
34권 1호 |
| 발표분야 |
기능성 고분자 |
| 제목 |
Synthesis of Thermosensitive Nanoparticles Based on PNIPAAM Core and Chitosan Shell Structure |
| 초록 |
New thermosensitive nanogels, PNIPAAm-AA conjugated with low molecular weight water soluble chitosan(LMWSC), were designed and synthesized for the controlled release of the loaded drug. PNIPAAm nonogels containing carboxylic group on their surface was synthesized using emulsion polymerization. The carboxylic groups were applied to conjugate with the amino group of the LMWSC. The particle size of synthesized nanogels was varied from 380 nm to 25 nm as temperature of the dispersed medium increased. LMWSC-conjugated nanogels of 2wt% MBA, crosslinking monomer, leaded to a stable aqueous dispersion at concentration of 1mg/1ml otherwise showed gel collapse temperature. The effect of temperature on the dynamic behavior of the PNIPAAm chains were also studied by 1H-NMR and fluorescent measurements. |
| 저자 |
정현, 김양배, 허선행, 남정표, 김동곤, 정영일, 장미경, 나재운
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| 소속 |
순천대 |
| 키워드 |
Core-shell; LMWSC; Lower critical solution temperature; Thermosensitive.;
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| E-Mail |
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