| 학회 | 한국고분자학회 |
| 학술대회 | 2002년 봄 (04/12 ~ 04/13, 서울대학교) |
| 권호 | 27권 1호, p.303 |
| 발표분야 | 의료용 고분자 부문위원회 |
| 제목 | Fabrication of Poly(MPC-co-EHMA)/Poly(L-lactide-co-glycolide) Scaffold |
| 초록 | Recently, poly(lactide-co-glycolide) (PLGA) is extensively used or tested for a wide range due to good biocompatibility, controllable biodegradability, and relatively good processability. PLGA was blended with poly(ω-methacryloyloxyethyl phosphorylcholine-co-ethylhexymethacrylate) (PMEH) (PLGA/PMEH) to endow with new functionality i.e., to improve wettability. PMEH polymer with 30 mole percent of MPC and 70 mole percent of 2-ethylhexylmethacrylate (EHMA) were prepared by a conventional radical polymerization technique and purified twice by reprecipitation from acetonitrile. PLGA/PMEH scaffolds were prepared by novel solvent casting/particle leaching and emulsion freezing drying methods and then compared. We observed the improvement of wettability of PLGA/PMEH scaffold with 0.01 w/v % brilliant blue dye dropping method. Characterizations of PLGA/PMEH scaffold were analyzed by SEM, mercury porosimeter, GPC, XRD, DSC and so on. Acknowledgement: This study was supported by MOWH(IMT-2000, 01-PJ11-PG9-01NT00-0011). |
| 저자 | 김인영1, 신필경2, 이 봉3, 강길선*4, 이해방**5, Yasuhiko Iwasaki***, Kazuhiko Ishihara**** |
| 소속 | 1부경대, 2*전북대, 3**한국화학(연), 4***동경 치의과 대, 5****동경대 |
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