| 학회 |
한국고분자학회 |
| 학술대회 |
2008년 가을 (10/09 ~ 10/10, 일산킨텍스) |
| 권호 |
33권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 |
| 제목 |
Bacterial adhesion, cell adhesion, andbiocompatibility of Nafion films. |
| 초록 |
We investigated bioadhesion (bacterial and cell adhesion) and biocompatibility of poly(tetrafluoroethylene-co-perfluoro-3,6-dioxa-4-methyl-7-octenesulfonicacid)(NafionTM)and compared the results with those of poly(vinylidenefluoride-co-hexafluoropropylene)(PVFHFP). When incubated with bacteria for 4h to 7days, Nafion film exhibited scarce bacterial adhesion at 6h. Incontrast, significant bacterial adhesion to PVFHFP film was observed at 4h. Although HEp-2 human cells adhered normally to both films, the cells adhered to Nafion appeared more lively and stable than those to PVFHFP. Subcutaneous implantation in mice revealed that Nafion has excellent biocompatibility in mice. PVFHFP, however, provoked a moderate and prolonged acute inflammatory response. In summary, Nafion is suitable for use in biomedical applications that require biocompatibility with a reduced possibility of post-operative infections. |
| 저자 |
김미희1, 이문호1, 김가희1, 정정운1, 김희수2
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| 소속 |
1포항공과대, 2동국대 |
| 키워드 |
Nafion film; perfluorinated polymer; bacterial adhesion; cell adhesion; biocompatibility; water sorption; water contact angle
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| E-Mail |
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