| 학회 |
한국고분자학회 |
| 학술대회 |
2018년 봄 (04/04 ~ 04/06, 대전컨벤션센터) |
| 권호 |
43권 1호 |
| 발표분야 |
고분자가공/복합재료 |
| 제목 |
Preparation of Mechanically Stable κ-Casein Fibrils and Microcapsules via the Layer-by-Layer Deposition |
| 초록 |
Amyloid fibrils are naturally occurring insoluble protein aggregates induced by the cross β-sheet stacking. We induced κ-casein fibrils under thermal incubation in reducing condition, and traced the fibril growth with thioflavin T assay and atomic force microscopy (AFM). Fluorescent intensity increased as κ-casein fibrils were formed and finally assembled fibrils were few hundreds of nanometers long. We analyzed the mechanical strength of the assembled fibrils with the AFM nano-indentation method. Assembled fibrils were found to have several GPa moduli comparable to naturally occurring strong materials such as collagen and silk. We fabricated stable hollow microcapsules by electrostatic interactions taking advantage of strong mechanical properties of the κ-casein fibrils. Hollow microcapsules were successfully prepared due to both strong molecular interactions and mechanically strong κ-casein fibrils. |
| 저자 |
이주봉1, 이지혜1, 염봉준2, 차국헌1
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| 소속 |
1서울대, 2명지대 |
| 키워드 |
layer-by-layer assembly; κ-casein fibril(s); amyloid(s); microcapsule(s); multilayer film(s)
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| E-Mail |
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