| 학회 |
한국공업화학회 |
| 학술대회 |
2019년 가을 (10/30 ~ 11/01, 제주국제컨벤션센터(ICC JEJU)) |
| 권호 |
23권 2호 |
| 발표분야 |
(콜로이드·계면화학) 무기물 기반 콜로이드 물질의 제조와 응용 |
| 제목 |
2D Transition Metal Dichalcogenide Antioxidants for Prolonged ROS Scavenging |
| 초록 |
Owing to the physiological and pathophysiological roles of reactive oxygen species (ROS), there is an increasing demand to regulate the concentration of ROS in biological processes. Herein, we present a novel approach for the exfoliation and functionalization of transition metal dichalcogenides (TMDs) in water via modulation of the hydrophobic interaction between poly(ε-caprolactone)-b-poly(ethylene glycol) (PCL-b-PEG) and the basal planes of TMDs. Decreasing the hydrophobic PCL length of PCL-b-PEG significantly increases the exfoliation efficiency of TMD nanosheets because of the increased polymer–TMD hydrophobic interaction. The TMD nanosheets exfoliated by PCL460-b-PEG5000 show excellent and prolonged scavenging activity for ROS, but each type of TMD displays a different scavenging tendency against hydroxyl and superoxide radicals. As-prepared 460-TMDs are able to effectively scavenge ROS in HaCaT human keratinocytes, and also exhibit excellent biocompatibility. |
| 저자 |
김종호 |
| 소속 |
한양대 |
| 키워드 |
antioxidant; liquid-phase exfoliation; transition metal dichalcogenide; ROS scavenging
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| E-Mail |
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