초록 |
Visual detection is an attractive method because it is possible to get qualitative information about analyte adsorption in real time without any expensive equipment. In this regard, many target-responsive hydrogel based on structural change of a hydrogel upon target addition have been proposed. In this study, we present novel protein-responsive hydrogel system. This system allows visual detection through bending angle change of hydrogel film on one-side inverse opal structure during BSA binding. A bending angle corresponding to binding capacity of hydrogel film found to be -0.18゚µg-1 in 12.32-73.52 µg. Furthermore, several other proteins were also used to confirm selective recognition. The bending angle of the hydrogel showed more significant changing in BSA solution compared to other protein solution owing selective adsorption. Thus, our concept is suited to detect template protein from actuation response of the hydrogel corresponding to the protein adsorption. |