| 학회 |
한국고분자학회 |
| 학술대회 |
2019년 가을 (10/09 ~ 10/11, 제주컨벤션센터) |
| 권호 |
44권 2호 |
| 발표분야 |
기능성 고분자 |
| 제목 |
Nanobiosensor comprising conducting polymer enclosed with polymeric vesicles for Selective detection of Influenza A virus |
| 초록 |
Nanobiosensor has been selected as a method for detecting wide range of pathogens to prevent pandemic emergence. As one of promising platform, conductive polymer based nanobiosensor has a distinct advantage in the way that its ability to sensitive and rapid detection. In this study, we designed a detection system which is conductive poly (aniline-co-pyrrole) based on polymersome conjugated with peptide for specific recognition of influenza A virus. We synthesized poly (aniline-co-pyrrole) polymerized within a polymersome consist of methoxy polyethylene glycol-block- polyphenylalanin co-polymer. Then we conjugated the polymersome with peptide binding to influenza virus. In the presence of Influenza virus, the peptide conjugated polymersome aggregated with the virus, which it induced absorption wave length change of the nanoparticle observed by UV-vis spectrophotometer. These results indicate that this nanobiosensor could be a potential candidate in terms of detecting influenza virus. |
| 저자 |
박근선1, 김현욱2, 임종우1, 박채원1, 함승주1
|
| 소속 |
1연세대, 2고려대 |
| 키워드 |
virus detection; conducting polymer; polymeric vesicles
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| E-Mail |
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