화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2019년 가을 (10/30 ~ 11/01, 제주국제컨벤션센터(ICC JEJU))
권호 23권 2호
발표분야 포스터_생체재료
제목 Tri-Functional Multilayer Nanoparticles with Fluorescent Silica Shell for Bioapplications
초록 We developed a new method of synthesis of layers of SERS-fluorescent light with magnetic properties in NP including fluorescent silica. In this study, we synthesized magnetic-fluorescence-SERS tri-function nanoprobes (MF-SERS) with clustered superparametric Fe3O4 nanoparticles (NPs), silver NPs, and fluorescent silica layers. We can see the strong SERS signal of silver NPs in MF-SERS particles, and we can see magnetic properties and fluorescence. This MF-SERS particle then shows the SERS signal and fluorescence in the cell and facilitates separation by using magnetic properties. We confirmed that the MF-SERS particles bonded to CD44 antibodies could be selective in detecting MDA-MB-231 cells. these results is, MF-SERS particles have proved to be useful nanopropes for bioapplication and hybrids multiple detection analysis.
저자 조아라, 안재현, 성보미, 김윤희, 함은일, 전봉현
소속 건국대
키워드 Multifunctional nanoparticles; Surface enhanced Raman scattering; Fluorescence nanoparticle; Superparamagnetism; Cell separation
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