| 학회 |
한국고분자학회 |
| 학술대회 |
2012년 가을 (10/11 ~ 10/12, 창원컨벤션센터) |
| 권호 |
37권 2호 |
| 발표분야 |
고분자구조 및 물성 |
| 제목 |
3-Dimensional Structure of Apoferritin and Ferritin in Nature : Self-assembly and Disassembly Behaviors |
| 초록 |
We investigated the structures of apoferritin and the ferritin core in a neutral solution by X-ray scattering measurements. Under neutral conditions, apoferritin assumed an intact hollow spherical structure. The structure included 24 homologous subunits (to form a 24-mer). The intact hollow spherical of apoferritin was stable over the pH range 3.40-10.0. Below pH 3.40, apoferritin became unstable and underwent stepwise disassembly through several structural intermediates. Structural recovery of the intermediates during the pH-induced reassembly process depended on the history of the disassembly process. The ferrihydrite core of ferritin under neutral conditions assumed a compact globular structure. The ferrihydrite core (i.e., the ferritin core) was stable over the pH range 2.10-10.0. |
| 저자 |
이진석, 김미희, 노예철, 안병철, 정정운, 권원상, 김경태, 고용기, 정성민, 권경호, 김영용, 김종현, 송성진, 위동우, 이문호
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| 소속 |
포항공과대 |
| 키워드 |
Ferritin; X-ray scattering; Self-assembly
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| E-Mail |
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