The solubilities of beta,beta-carotene-4,4'-dione (canthaxanthin) in methanol, ethanol, acetone, ethyl acetate, toluene, cyclohexane, 1,2-dichloroethane, and trichloromethane were measured by a synthetic method over the temperature range from (293.15 to 343.15) K at atmospheric pressure. A laser monitoring observation technique was employed to determine the dissolution of the solid phase in a solid-liquid system. The experimental solubilities were fitted by the modified Apelblat equation with the deviation less than 2.7 %.