The solubility of (+)-(S)-2-(6-methoxynaphthalen-2-yl) propanoic acid {otherwise commonly known as (S)-Naproxen} in pure methanol, ethanol, acetone, ethyl ethanoate, and propan-2-ol was measured at temperature ranging from (278 to 320) K at atmospheric pressure. A laser monitoring observation technique was used to determine the dissolution of the solid phase in a solid + liquid mixture. The experimental solubility data were correlated with a semiempirical Apelblat equation.