화학공학소재연구정보센터
홈 로그인 로그아웃 연락처 사이트맵
Macromolecular Research, Vol.20, No.10, 1083-1087, October, 2012
DOI10.1007/s13233-012-0149-4  Export Citation
Synthesis of Dendrimers via Staudinger/Aza-Wittig Reaction of Frechet-Type Dendritic Benzyl Azides and Frechet-Type Dendritic Benzaldehydes
Seung Choul Han, Jae Wook Lee†, and Sung-Ho Jin1, †
  • Department of Chemistry and Department of Medical Bioscience, Dong-A University, Busan, 604-714, Korea
  • 1Department of Chemistry Education, Pusan National University, Busan, 609-735, Korea
E-mail:,
A synthetic strategy for dendrimers was developed using Staudinger/aza-Wittig reaction with an aldehyde and an azide in the presence of triphenylphosphine, followed by the reduction of imine intermediates. A fusion method between Frechet-type dendritic benzaldehydes and Frechet-type dendritic benzyl azides led to the formation of first-through fourth-generation dendrimers containing secondary amine as a connector in high yields. Further, fusion coupling using different generation dendrons afforded, efficiently, the unsymmetrical dendrimers. The obtained dendrimers were characterized by the analyses of 1H and 13C NMR spectroscopy, IR spectroscopy, mass spectra, and gel permeation chromatography (GPC) analysis.
Keywords:aldehyde;azide;dendrimer;Staudinger/aza-Wittig reaction.
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