CaO-SiO 2 -PEEK 생체복합체의 제조와 in-vitro 특성평가

김일용; 조성백; 김종옥; 신종우; 이성호; 박중근; 김택남; Ill Yong Kim; Sung Baek Cho; Jong Ock Kim; Jong Woo Shin; Sung Ho Lee; Joong Keun Park; Taik Nam Kim

Korean Journal of Materials Research, Vol.14, No.4, 287-292, April, 2004

DOI10.3740/MRSK.2004.14.4.287 Export Citation

CaO-SiO 2 -PEEK 생체복합체의 제조와 in-vitro 특성평가

Preparation of CaO-SiO 2 -PEEK bio-composites and in-vitro Evaluation

김일용^†, 조성백¹, 김종옥, 신종우, 이성호², 박중근³, 김택남

배재대학교 대학원 재료공학과
¹한국지질자원연구원 자원활용 소재연구부
²대전보건대학교 치기공과
³한국과학기술원 재료공학과

Ill Yong Kim^†, Sung Baek Cho¹, Jong Ock Kim, Jong Woo Shin, Sung Ho Lee², Joong Keun Park³, and Taik Nam Kim

Department of Materials Engineering, Graduate School of Paichai University, 439-6, Doma2-dong, Seo-gu, Daejeon, 302-162, Korea
¹Mineral & Materials Processing Division, Korea Institute of Geoscience and Mineral Resources(KIGAM), 30, Kajung-dong, Yuseong-Gu, Daejeon 305-350, Korea
²Dept. of Dental Laboratory, Daejeon Health Science College, 77-3, Gayang2-dong, Dong-gu, Daejeon, 300-711, Korea
³Department of Materials Science & Engineering, KIST, 373-1, Guseong-dong, Yuseong-gu, Daejeon, 305-701, Korea

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A bio-composites were prepared by mechanical mixing with bioactive sol-gel derived CaO?SiO 2 and organic PEEK for bone repairing hybrid materials. The composites were characterized by in-vitro test. A bonelike apatite was formed on the surface of all bio-composites in SBF test. The cell morphology and adhesion on the surface of the composites having below 30% PEEK were clearly observed in L929 cell experiment.

Keywords:CaO-SiO 2;polyetheretherketone;organic-inorganic;hybrid;cell test

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[1] Hench LL, Splinter RJ, Allen WC, Greenlee TK, J. Biomed. Res. Symp., 2, 117 (1971)

[2] Hench LL, J. Am. Ceram. Soc., 74, 1487 (1991)

[3] Kokubo T, Biomaterials, 12, 155 (1991)

[4] Lee SK, Koo KM, Lee MH, Lee HD, Lee BK, J. Kor. Ceram. Soc., 40(6), 566 (2003)

[5] Kokubo T, Acta Mater., 46(7), 2519 (1998)

[6] Oyane A, Nakanishi K, Kim HM, Miyaji F, Kokubo T, Soga N, Nakamura T, Biomaterials, 20, 79 (1999)

[7] Kokubo T, Thermochim. Acta, 280-281, 479 (1996)

[8] Zhang K, Wang Y, Hillmyer MA, Francis LF, Biomaterials, 25(13), 2489 (2004)

[9] Rhee SH, Biomaterials, 25, 1167 (2004)

[10] Miyata N, Fuke K, Chen Q, Kawashita M, Kokubo T, Nakamura T, Biomaterials, 23, 3033 (2002)

[11] Abu Baker MS, Cheang P, Khor KA, J. Mater. Proce. Tech., 89-90, 462 (1999)

[12] Ha SW, Hauert R, Ernst KH, Wintermantel E, Surf. & Coat. Tech., 96, 293 (1997)

[13] Tan KH, Chua CK, Leong KF, Cheah CM, Cheang P, Abu Baker MS, Cha SW, Biomaterials, 24, 3115 (2003)

[14] Kamitakahara M, Kawashita M, Kokubo T, Nakamura T, Biomaterials, 22, 3191 (2001)