화학공학소재연구정보센터
홈 로그인 로그아웃 연락처 사이트맵
Journal of Industrial and Engineering Chemistry, Vol.108, 418-428, April, 2022
DOI10.1016/j.jiec.2022.01.018  Export Citation
Pressurized liquid extraction of phenolics from Pseuderanthemum palatiferum (Nees) Radlk. leaves: Optimization, characterization, and biofunctional properties
Truc Cong Ho1, Anley Teferra Kiddane2, Fazlurrahman Khan3, Yeon-Jin Cho1, Jin-Seok Park1, Hee-Jeong Lee1, Gun-Do Kim2, Young-Mog Kim1, 3, and Byung-Soo Chun1, †
  • 1Department of Food Science and Technology, Pukyong National University, Busan 48513, Republic of Korea
  • 2Department of Microbiology, Pukyong National University, Busan 48513, Republic of Korea
  • 3Research Center for Marine Integrated Bionics Technology, Pukyong National University, Busan 48513, Republic of Korea
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In this study, the pressurized liquid extraction (PLE) of total phenolic content (TPC), gallic acid (GA), and p-hydroxybenzoic acid (PHBA) from Pseuderanthemum palatiferum (Nees) Radlk. leaves was optimized using response surface methodology. The extract at the optimum conditions of TPC, namely OP, was characterized using GC–MS, HPLC, and spectrophotometry analysis. Furthermore, bio-functional properties of the OP, including antioxidant, antimicrobial, antihypertensive activities, and cytotoxicity against cancer and normal cell lines, were also investigated. The results showed that all extraction models were appropriate in predicting the extraction processes (p < 0.05) of the target compounds. In addition to TPC, GA, and PHBA, the OP also contains a high amount of other valuable components that contributed to its highly biological activities. Moreover, the OP was nontoxic on HaCaT cells with a concentration of no more than 1000 mg/mL. From the obtained results, PLE proved to be a suitable technique for the recovery of bioactive compounds from P. palatiferum leaves.
Keywords:Pressurized liquid extraction;Response surface methodology;Phenolics;Biofunctional properties
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