무기계 항균제가 첨가된 고분자 치아수복재료의 물성 최적화

김오영; Ohyoung Kim

Journal of the Korean Industrial and Engineering Chemistry, Vol.11, No.6, 651-656, October, 2000

Optimization of Dental Properties of Polymeric Dental Restorative Composites Combined with Inorganic Antibacterial Agent

김오영 ^†

단국대학교 공학부, 고분자공학 전공, 서울 140-714

Ohyoung Kim^†

Department of Polymer Science & Engineering, Dankook University, Seoul 140-714, Korea

E-mail:

초록

은-지르코늄인산계(AZPA) 무기항균제와 키토산이 단독 혹은 혼합 첨가된 고분자계 치아수목재를 제조하였다. Resin matrix 내 충진재의 분산성 향상과 치아수복재의 기계적 특성을 향상시키기 위해 실리카 충진재 표면을 γ-methacryloxypropyltrimethoxysilane을 이용하여 소수성으로 처리하여 사용하였다. 제조된 치아수복재의 대표적 기계적 물성인 간접인장강도, 굴곡강도, Knoop 경도값 및 항균 특성에 대한 항균제의 효과를 고찰하였다. 그 결과, 사용된 resin matrix 인 2,2'-bis-[4-(3-methacryloxy-2-hydroxypropoxy)phenyl]propane/triethyleneglycoldimethacrylate (70/30 wt%)에 대한 충진재의 충진률이 60 wt%일 때 AZPA의 함량이 충진재를 기준으로 2∼4 wt%일 때가 최적의 물성을 보임을 알 수 있었다. 또한 키토산을 혼합 사용한 경우 수복재의 기계적 물성의 큰 변화없이 항균특성이 매우 향상됨을 알 수 있었다.

The preparation of antibacterial polymeric dental restorative composites was carried out using silver/zirconium-phosphoric acid(AZPA) inorganic antibacterial agent and chitosan. In order to improve the mechanical properties of dental composites, initially, the surface of fumed silica microfiller was treated with γ-methacryloxypropyltrimethoxysilane. Diametral tensile strength, flexural strength, Knoop hardness, antibacterial, and antifungal properties of dental composites were investigated. The optimum concentration of AZPA was 2∼4 wt% of silica filler used based on 60 wt% of loading onto 2.2'-bis-[4-(3-methacryloxy-2-hydroxypropoxy)phenyl]propane/triethyleneglycoldimethacrylate (70/30 wt%) resin matrix. Addition of chitosan to AZPA enhanced the antibacterial properties of restorative materials.

Keywords:Silver/zirconium-phosphoric acid;Dental restorative composites;Diametral tensile strength;Flexural strength;Antibaterial

[References]

Choi Y, Kim K, J. Korea Res. Soc. Dent. Mater., 22(1), 7 (1995)
김경현, 권오승, 김현기, 백규철, 엄정문, 권혁춘, 대한치과보존학회지, 22(1), 35 (1997)
치의신보, 1996년 1월 6일자, 21면, 22면 (1996)
Jang J, Kim S, Polym. J., 28(4), 293 (1996)
Jang J, Kim SW, Polym.(Korea), 18(4), 584 (1994)
Kim OY, Appl. Chem., 2(1), 68 (1998)
Korean Patent, 98-014318 (to Hansol Paper Co.) (1998)
Phillips RW, Skinner's Science of Dental Materials, 8th ed., Igaku-Shoin/Saunders, 177 (1982)
Craig RG, Restorative Dental Materials, 8th ed., CV Mosby, St. Louis, U.S.A., 514 (1989)
Japanese Patent, 93-85915 (to Kuraray Co.) (1993)
Jedrychowski JR, Caputo AA, Kerper S, J. Oral Rehabilitation, 10, 373 (1983)
Takemura K, Sakamoto Y, Jpn. J. Conserv. Dent., 26, 540 (1983)
Muzzarelli RAA, Chitin, Pengamon, New York (1977)
Wolform ML, Madison RK, Cron MJ, J. Am. Chem. Soc., 74, 1491 (1952)
Willems G, Lambrechts P, Braem M, Celis JP, Vanherle G, Dental Mater., 8, 310 (1992)
Kim SW, Jang JS, Polym. Eng. Sci., 38(7), 1142 (1998)
Council on Dental Materials and Devices, American Dental Association Spec. No. 27 for Direct Filling Resins, J. Am. Dent. Association, 94, 115 (1977)
ISO 3336, Dentistry-Synthetic Polymer Teeth (1993)
ISO 846, Plastics-Determination of Behaviour under the Action of Fungi and Bacteria-Evaluation by Visual Examination or Measurement of Change in Mass or Physical Properties (1978)
Atlas RM, Brown AE, Dobra KW, Miller L, Experimental Microbiology-Fundamentals and Applications: Exercise 16, Macmillan Pub. Co., New York, 109 (1984)
ASTM G 21-90, Standards Practice for Determining Resistance of Synthetic Polymeric Materials to Fungi (1990)
Kim O, Kwon O, Appl. Chem., 2(2), 700 (1998)
Kim O, Res. Inst. Ind. Tech. Res. Papers, Dankook Univ., 1, 77 (1999)
Kim O, Appl. Chem., 3(2), 9 (1999)

[Referenced By]

[Related Articles]

[1] Choi Y, Kim K, J. Korea Res. Soc. Dent. Mater., 22(1), 7 (1995)

[2] 김경현, 권오승, 김현기, 백규철, 엄정문, 권혁춘, 대한치과보존학회지, 22(1), 35 (1997)

[3] 치의신보, 1996년 1월 6일자, 21면, 22면 (1996)

[4] Jang J, Kim S, Polym. J., 28(4), 293 (1996)

[5] Jang J, Kim SW, Polym.(Korea), 18(4), 584 (1994)

[6] Kim OY, Appl. Chem., 2(1), 68 (1998)

[7] Korean Patent, 98-014318 (to Hansol Paper Co.) (1998)

[8] Phillips RW, Skinner's Science of Dental Materials, 8th ed., Igaku-Shoin/Saunders, 177 (1982)

[9] Craig RG, Restorative Dental Materials, 8th ed., CV Mosby, St. Louis, U.S.A., 514 (1989)

[10] Japanese Patent, 93-85915 (to Kuraray Co.) (1993)

[11] Jedrychowski JR, Caputo AA, Kerper S, J. Oral Rehabilitation, 10, 373 (1983)

[12] Takemura K, Sakamoto Y, Jpn. J. Conserv. Dent., 26, 540 (1983)

[13] Muzzarelli RAA, Chitin, Pengamon, New York (1977)

[14] Wolform ML, Madison RK, Cron MJ, J. Am. Chem. Soc., 74, 1491 (1952)

[15] Willems G, Lambrechts P, Braem M, Celis JP, Vanherle G, Dental Mater., 8, 310 (1992)

[16] Kim SW, Jang JS, Polym. Eng. Sci., 38(7), 1142 (1998)

[17] Council on Dental Materials and Devices, American Dental Association Spec. No. 27 for Direct Filling Resins, J. Am. Dent. Association, 94, 115 (1977)

[18] ISO 3336, Dentistry-Synthetic Polymer Teeth (1993)

[19] ISO 846, Plastics-Determination of Behaviour under the Action of Fungi and Bacteria-Evaluation by Visual Examination or Measurement of Change in Mass or Physical Properties (1978)

[20] Atlas RM, Brown AE, Dobra KW, Miller L, Experimental Microbiology-Fundamentals and Applications: Exercise 16, Macmillan Pub. Co., New York, 109 (1984)

[21] ASTM G 21-90, Standards Practice for Determining Resistance of Synthetic Polymeric Materials to Fungi (1990)

[22] Kim O, Kwon O, Appl. Chem., 2(2), 700 (1998)

[23] Kim O, Res. Inst. Ind. Tech. Res. Papers, Dankook Univ., 1, 77 (1999)

[24] Kim O, Appl. Chem., 3(2), 9 (1999)