The calixarene which are macrocycles with enfroced interior large enough to imprioson. ion and molecular, for using host-guest complex or enzyme mimic. Especially in nature sulfate and phosphate binding proteins are very important receptors for the active transport systems in the cell. In this paper we report the syntheses of new cavitand 4 derivatives containing four urea groups by anions receptors. Their structures were determined by spectroscopic studies.