In this paper, we consider the problem of robust control for uncertain sampled-data systems that possess random jumping parameters which is described by a finite-state Markov process. The conditions for the existence of a stabilizing control and optimal control for the underlying systems are obtained. The desired controllers are designed which are in terms of matrix inequalities. Finally, a numerical example is given to show the potential of the proposed techniques. (c) 2006 Elsevier Ltd. All rights reserved.