The precursors of mesoporous titania were synthesized via supra-molecular self-assembly route induced by composite templates (CTAB/P-123) from industrial titanyl sulfate solution under ultrasonic irradiation, microwave and hydrothermal condition. The hydrolysis and polycondensation rates of TiOSO4 solution were controlled by adjusting the pH value at about 1.0. Mesoporous titania with anatase phase was obtained after templates removal by calcinations. The as-prepared powder was characterized by X-ray diffraction (XRD), N-2 isothermal adsorption-desorption, HRTEM and SAD. External outfields with enhancing polar action and soft hydrothermal condition were beneficial to prepare better mesoporous TiO2. Ultrasonic vibration promoted the formation of mesoporous structure. Under microwave irradiation, mesoporous TiO2 was synthesized with BET specific surface area of 190.6 m(2) g(-1), average pore diameter of 2.57 nm and crystal size of 13.65 nm. And ultrasonic irradiation, microwave and hydrothermal conditions were making for forming and stabilizing the mesoporous structure. (C) 2008 Elsevier B.V. All rights reserved.