Journal of the American Chemical Society, Vol.132, No.16, 5562-5562, 2010
Palladium-Catalyzed Asymmetric Addition of Diarylphosphines to Enones toward the Synthesis of Chiral Phosphines
An asymmetric addition of diarylphosphines to B-substituted enones under mild conditions using a chiral pincer-palladium catalyst has been developed for the synthesis of chiral phosphines with excellent stereoselectivity (up to 99% ee).