A chemiluminescence (CL) method is reported for the determination of melamine by flow injection analysis (FIA). This method is based on the reaction of melamine with Ru(bipy)3 2+ and Ce(IV) in presence of colloidal platinum nanopartilces to produce CL. Under optimal condition, CL intensity was linearly related with melamine concentration. The calibration curve was linear over the range of 5.0×10^(-9) - 2.0×10^(-6) M with the limit of detection, 9.8×10^(-9) M. The relative standard deviation of 1.0× 10^(-7) M melamine was found 2.5% (n=10).