The effect of Sc, Pr, and Ce co-doping on the emission and scintillation properties of lutetium aluminum epitaxial garnet layers, Lu3Al5O12 (LuAG), was studied. The Sc and Pr co-doped garnets with optimized dopant content provide in many aspects better emission and scintillation response compared to those without Sc co-doping. Energy transfer from sensitizer Sc3+ to activator Pr3' ions was observed for small Sc doping levels, which consequently resulted in increased radioluminescence intensity and photoelectron yield. At higher Sc content above 3 at%, however, the Pr3+ emission was partly quenched. Considerable suppression of slow components and notable increase of fast components in the photoelectron yield was the most remarkable effect of the Sc co-doping in PrSc:LuAG. (C) 2010 Elsevier B.V. All rights reserved.