화학공학소재연구정보센터
홈 로그인 로그아웃 연락처 사이트맵
Korea-Australia Rheology Journal, Vol.27, No.1, 1-10, February, 2015
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Effect of cholesterol and triglycerides levels on the rheological behavior of human blood
Leonardo Moreno, Fausto Calderas†, Guadalupe Sanchez-Olivares1, Luis Medina-Torres2, Antonio Sanchez-Solis, and Octavio Manero
  • Instituto de Investigaciones en Materiales, Universidad Nacional Autónoma de México, A.P. 70-360, México, D.F., 04510, Mexico
  • 1CIATEC, A.C. Omega 201, Industrial Delta, CP 37545, León, Gto, Mexico
  • 2Departamento de Ingeniería Química, Facultad de Química, UNAM, Mexico
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Important public health problems worldwide such as obesity, diabetes, hyperlipidemia and coronary diseases are quite common. These problems arise from numerous factors, such as hyper-caloric diets, sedentary habits and other epigenetic factors. With respect to Mexico, the population reference values of total cholesterol in plasma are around 200 mg/dL. However, a large proportion has higher levels than this reference value. In this work, we analyze the rheological properties of human blood obtained from 20 donors, as a function of cholesterol and triglyceride levels, upon a protocol previously approved by the health authorities. Samples with high and low cholesterol and triglyceride levels were selected and analyzed by simplecontinuous and linear-oscillatory shear flow. Rheometric properties were measured and related to the structure and composition of human blood. In addition, rheometric data were modeled by using several constitutive equations: Bautista-Manero-Puig (BMP) and the multimodal Maxwell equations to predict the flow behavior of human blood. Finally, a comparison was made among various models, namely, the BMP, Carreau and Quemada equations for simple shear rate flow. An important relationship was found between cholesterol, triglycerides and the structure of human blood. Results show that blood with high cholesterol levels (400 mg/dL) has flow properties fully different (higher viscosity and a more pseudo-plastic behavior) than blood with lower levels of cholesterol (tendency to Newtonian behavior or viscosity plateau at low shear rates).
Keywords:blood rheology;cholesterol;triglycerides;BMP constitutive equation
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