화학공학소재연구정보센터
홈 로그인 로그아웃 연락처 사이트맵
Journal of Industrial and Engineering Chemistry, Vol.101, 205-213, September, 2021
DOI10.1016/j.jiec.2021.06.011  Export Citation
A shelf-life study of silica- and carbon-based mesoporous materials
Emma M. Björk1, 2, †, Aylin Atakan1, 2, Pei-Hsuan Wu3, Alessandra Bari4, Carlotta Pontremoli4, Kai Zheng5, Dimitra Giasafaki6, Giorgio Iviglia7, Elisa Torre7, Clara Cassinelli7, Marco Morra7, Theodore Steriotis6, Georgia Charalambopoulou6, Aldo R. Boccaccini5, Sonia Fiorilli4, Chiara Vitale-Brovarone4, Fredrik Robertsson3, and Magnus Odén1, 2
  • 1Nanostructured Materials, Dept. of Physics, Chemistry and Biology, Linkoping University, 581 83 Linköping, Sweden
  • 2Nanolith Sverige AB, Ferievägen 15, 168 41 Bromma, Sweden
  • 3Nanolith Sverige AB, Ferievagen 15, 168 41 Bromma, Sweden
  • 4Department of Applied Science and Technology, Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129 Torino, Italy
  • 5Institute of Biomaterials, University of Erlangen-Nuemberg, 91058 Erlangen, Germany
  • 6National Centre for Scientific Research ‘‘Demokritos”, Agia Paraskevi Attikis, 15341 Athens, Greece
  • 7Nobil Bio Ricerche srl, Via Valcastellana 26, 14037 Portacomaro (Asti), Italy
E-mail:
Mesoporous silica- and carbon-based materials, including bioactive glasses, have proven potential as components of medical devices and as drug carriers. From an application perspective, knowledge about the shelf-life stability of these materials under various conditions is vital. Here, mesoporous bioactive glasses (MBGs) synthesized by aerosol-assisted spray-drying and by a batch sol.gel method, mesoporous silicas of SBA-15 type, and mesoporous carbons CMK-1 and CMK-3 have been stored under varying conditions, e.g. at different temperature and relative humidity (RH), and in different storage vessels. The results show that the silica-based materials stored in Eppendorfs are sensitive to humidity. Spray dried MBGs decompose within 1 month at a RH >5%, whilst sol.gel MBGs are more stable up to a RH >60%. Changing the storage vessel to sealed glass flasks increases the MBGs lifetime significantly, with no degradation during 2 months of storage at a RH = 75%. SBA-15 stored in Eppendorfs are more stable compared to MBGs, and addition of F- ions added during the synthesis affects the material degradation rate. Mesoporous carbons are stable under all conditions for all time points. This systematic study clearly demonstrates the importance of storage conditions for mesoporous materials which is crucial knowledge for commercialization of these materials.
Keywords:Mesoporous bioactive glass;Mesoporous silica;Mesoporous carbon;Materials stability;Shelf-life
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