시린지리스 전기방사를 통한 부직포 기반 건조 콜라겐 마스크팩 제조

정한진; 이소연; 윤재중; 이경진; Hanjin Jeong; Soyeon Lee; Jeajoong Youn; Kyung Jin Lee

Polymer(Korea), Vol.46, No.3, 355-360, May, 2022

DOI10.7317/pk.2022.46.3.355 Export Citation

시린지리스 전기방사를 통한 부직포 기반 건조 콜라겐 마스크팩 제조

Preparation of Dried Collagen Mask Sheet Based on Non-woven Mat via Syringeless Electrospinning

정한진, 이소연, 윤재중¹, 이경진^†

충남대학교 응용화학공학과
¹Y&K 헬스케어

Hanjin Jeong, Soyeon Lee, Jeajoong Youn¹, and Kyung Jin Lee^†

Department of Chemical Engineering and Applied Chemistry, College of Engineering, Chungnam National University, 99 Daehak-ro (st), Yuseong-gu, Daejeon 34134, Korea
¹Y&K HEALTHCARE Co., Ltd, Je3gongdan 2-gil, Seounmyeon, Anseong-si, Gyeonggi-do 17605, Korea

E-mail:

초록

마스크 팩은 다양한 유효 물질을 함유하며 피부 개선을 위해 이용되고 있으나, 최근 1회용 플라스틱 지지체 이용의 최소화를 위해 건조 형태의 마스크 팩에 대한 많은 연구가 진행되고 있다. 본 연구에서는 유효 물질인 저분 자량 콜라겐과 고분자량 히알루론산을 기반으로 하여 시린지리스 전기방사를 통해 나노 섬유 부직포를 제조하였다. 이를 통해 마스크 팩의 표면적을 향상시키고 유효 물질의 전달 속도를 개선하고자 하였다. 고분자 용액 조성을 조 절하고 모폴로지를 관찰하여 전기 방사성이 용이하면서도 유효 물질인 콜라겐이 다량 함유된 부직포 기반 마스크 팩을 제조할 수 있었다. 또한 물 분사 시 건조된 콜라겐 부직포가 용해되는 것을 통해 건조 마스크 팩으로서의 응 용 가능성을 확인하였다.

The mask sheet containing various effective materials have been widely used for skin improvement over last decades. Recently due to the efforts on reduction of plastic waste, many studies have been conducted to develop dried-type mask sheets. In this study, nanofiber nonwoven was prepared via syringeless electrospinning of collagen (low molecular weight (Mw)) which is effective materials for skin and hyaluronic acid (high Mw) as a supporter. By controlling the composition of the polymer solution and observing the morphology, optimized electrospinning condition have been achieved for mass-production of dry-type mask pack containing large amount of collagen. Through dissolving collagen when water mist is sprayed on the nonwoven, possibility for application to dry-type mask have been also presented.

Keywords:collagen mask sheet;electrospinning;syringeless;colloid electrospinning

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[2] Morganti P, Morganti G, Chen H, Gagliardini A, J. Clin. Cosmet. Dermatol., 3, 1 (2019)

[3] Pei X, Yang R, Zhang Z, Xu Y, Han X, Wang J, Li Y, Chin. J. Prev. Vet. Med., 42, 235 (2008)

[4] Hong CA, Kim JS, Lee SH, Kong WH, Park TG, Mok H, Nam YS, Adv. Funct. Mater., 23, 316 (2013)

[5] Yun W, Lee Y, Kim D, Kim J, Sung J, Lee H, Son H, Hwang D, Jung Y, Text. Color. Finish., 29, 45 (2017)

[6] Kwak M, Go J, Kim J, Lee Y, Lee S, Lee H, Son H, Jung Y, Hwang D, Biomater. Res., 17, 91 (2013)

[7] Ajmeri MCJ, Mr JRA, Application of Nonwovens in Healthcare and Hygiene Sector. In Medical Textiles and Biomaterials for Healthcare, Anand SC, Kennedy JF, Miraftab M, Rajendran S, Eds.; Wordhead Publishing: Cambridge, pp 80-89, 2006.

[8] Li X, Cui R, Liu W, Sun L, Yu B, Fan Y, Feng Q, Cui F, Watari F, J. Nanomater., 2013, 728130 (2013)

[9] Ishchenko O, Plavan V, Resnytskyi I, Liashok I, Technol. Audit. Prod. Reserves, 5, 4 (2018)

[10] Moon S, Gil M, Lee KJ, Sci. Rep., 7, 41424 (2017)

[11] Jirsak O, Sanetrnik F, Lukas D, Kotek V, Martinova L, Chaloupek J, Method of Nanofibres Production from a Polymer Solution Using Electrostatic Spinning and a Device for Carrying Out the Method. US Patent 7,585,437, 2009.

[12] Moon S, Lee KJ, 9. Needless and Syringeless Electrospinning for Mass Production. In Green Electrospinning, Horzum, N., Demir, M. M., Muñoz-Espí, R., Crespy, D. Eds.; De Gruyter: Berlin, Boston, pp 217-238, 2019.

[13] Moon S, Yun J, Lee JY, Park G, Kim SS, Lee KJ, Macromol. Mater. Eng., 304, 1800564 (2019)

[14] Moon S, Park K, Seo E, Lee KJ, Macromol. Mater. Eng., 303, 1700565 (2018)

[15] Lee J, Lee KJ, Macromol. Mater. Eng., 307, 2100818 (2022)

[16] Fischer RL, McCoy MG, Grant SA, J. Mater. Sci. -Mater. Med., 23, 1645 (2012)

[17] Fan PW, Chen WL, Lee TH, Chiu YJ, Chen JT, Macromolecules, 45, 5816 (2012)

[18] Khan WS, Asmatulu R, Ceylan M, Jabbarnia A, Fibers Polym., 14, 1235 (2013)

[19] Porter RS, Johnson JF, Chem. Rev., 66, 1 (1966)

[20] Graessley WW, J. Chem. Phys., 47, 1942 (1967)

[21] Rubinstein M, Semenov AN, Macromolecules, 34, 1058 (2001)

[22] Shivokhin ME, Narita T, Talini L, Habicht A, Seiffert S, Indei T, Schieber JD, J. Rheol., 61, 1231 (2017)

[23] He JH, Wan YQ, Polymer, 45, 6731 (2004)

[24] Ferry JD, Viscoelastic Properties of Polymers; John Wiley & Sons: New Jersey, 1980.

[25] Soh YS, Polym. Korea, 12, 484 (1988)

[26] Morris ER, Rees DA, Welsh EJ, J. Mol. Biol., 138, 383 (1980)

[27] Zhan N, Li Y, Zhang C, Song Y, Wang H, Sun L, Yang Q, Hong XA, J. Colloid Interface Sci., 345, 491 (2010)

[28] Yarin AL, Koombhongse S, Reneker DH, J. Appl. Phys., 90, 4836 (2001)

[29] de Campos Vidal B, Mello MLS, Micron, 42, 283 (2011)

[30] Zhou Y, Yao H, Wang J, Wang D, Liu Q, Li Z, Int. J. Nanomedicine., 10, 3203 (2015)

[31] Jia W, Li M, Kang L, Gu G, Guo Z, Chen Z, J. Mater. Sci. -Mater. Med., 54, 10871 (2019)

[32] Yang K, Sun J, Wei D, Yuan L, Yang J, Guo L, Fan H, Zhang X, J. Mater. Chem. B, 5, 8707 (2017)